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The principal potassium channel in human sperm has not been conclusively characterized. While in mice, the potassium channel is Slo3, there is no consensus in the field regarding the identity of human KSper. The two candidates are Slo1 and Slo3, which have different sensitivities.

One of our research areas is trying to characterize human KSper.

Sperm ion channels

Figure from Mundt et al., 2018